MUC5AC antibody (AA 4848-5030)

Catalog No. ABIN3031872

This anti-MUC5AC antibody is a Rabbit Polyclonal antibody detecting MUC5AC in WB and IHC (p). Suitable for Human.

Quick Overview for MUC5AC antibody (AA 4848-5030) (ABIN3031872)

Target: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC5AC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MUC5AC Antibody

Binding Specificity: AA 4848-5030

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (4848-5030) was used as the immunogen for this MUC5AC antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the MUC5AC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the MUC5AC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for MUC5AC

Target: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Alternative Name: MUC5AC Mucin-5AC

Background: Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. It is mapped to 11p15.5. MUC5AC is highly expressed in adult trachea and stomach. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease(COPD). It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold. It is also a direct and critical mediator of resistance during intestinal nematode infection.

Gene ID: 4586