MPRIP antibody (N-Term)

Catalog No. ABIN3031920

This anti-MPRIP antibody is a Rabbit Polyclonal antibody detecting MPRIP in WB. Suitable for Human.

Quick Overview for MPRIP antibody (N-Term) (ABIN3031920)

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPRIP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MPRIP Antibody

Binding Specificity: N-Term

Purification: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human RIP3 (EVKAMASLDNEFVLRLE) was used as the immunogen for this RIP3 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the RIP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the RIP3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for MPRIP

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Alternative Name: RIP3

Background: Receptor-interacting serine/threonine-protein kinase 3(RIPK3), also known as RIP3, is an enzyme that in humans is encoded by the RIPK3 gene. This gene is mapped to 14q12. The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

UniProt: Q9Y572