MPRIP antibody (AA 550-600)

Catalog No. ABIN7450461

Product Details anti-MPRIP Antibody

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Binding Specificity: AA 550-600

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPRIP antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-MPRIP/M-RIP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 550 and 600

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MPRIP

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Alternative Name: MPRIP/M-RIP (MPRIP Products)

Synonyms: M-RIP antibody, MRIP antibody, RHOIP3 antibody, RIP3 antibody, p116Rip antibody, 9530046C02 antibody, AA536749 antibody, AI647711 antibody, C76423 antibody, Rhoip3 antibody, mKIAA0864 antibody, M-rip antibody, Mrip antibody, myosin phosphatase Rho interacting protein antibody, MPRIP antibody, Mprip antibody

Background: Background: MPRIP targets myosin phosphatase to the actin cytoskeleton. It is required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MPRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells [taken from the Universal Protein Resource (UniProt) Q6WCQ1].

Gene ID: 23164

UniProt: Q6WCQ1