Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CASP5 antibody (Center)

CASP5 Reactivity: Human IF, IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN303202
$765.60
Plus shipping costs $45.00
50 μg
Shipping to: United States
Available
  • Target See all CASP5 Antibodies
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Binding Specificity
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 52
    • 9
    • 7
    • 1
    • 1
    Human
    Host
    • 49
    • 3
    Rabbit
    Clonality
    • 42
    • 10
    Polyclonal
    Conjugate
    • 34
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This CASP5 antibody is un-conjugated
    Application
    • 33
    • 19
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purification
    Immunoaffinity Chromatography.
    Immunogen
    Synthetic peptide corresponding to 14 amino acid peptide from the center of human Caspase-5.
  • Application Notes
    Immunohistochemistry on Paraffin Sections (5 μg/mL). Immunocytochemistry. Western Blot (0.5-1 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate Buffered Saline PBS, containing 0.02 % Sodium Azide as preservative.
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer. Dilute only prior to immediate use.
  • Target
    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
    Alternative Name
    Caspase-5 (CASP5 Products)
    Synonyms
    ICE(rel)III antibody, ICEREL-III antibody, ICH-3 antibody, CASP5 antibody, caspase 5 antibody, caspase-5 antibody, CASP5 antibody, LOC100437308 antibody
    Background
    Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1b and IL-18. Caspase-5 can interact with caspase-1, both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1b. Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-g.Synonyms: CASP-5, CASP5, ICE(rel)-III, ICH-3 protease, ICH3, TY protease
    Gene ID
    838
    NCBI Accession
    NP_001129581
    UniProt
    P51878
    Pathways
    Inflammasome
You are here:
Support