ONECUT1 antibody (N-Term)

Catalog No. ABIN3032095

Product Details anti-ONECUT1 Antibody

Target: ONECUT1 (One Cut Homeobox 1 (ONECUT1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ONECUT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human ONECUT1/HNF6 (LGSIHNSQQGLPHYAHP) was used as the immunogen for this HNF6 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the HNF6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the HNF6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for ONECUT1

Target: ONECUT1 (One Cut Homeobox 1 (ONECUT1))

Alternative Name: HNF6 (ONECUT1 Products)

Synonyms: D9Ertd423e antibody, HNF-6 antibody, Hfh12 antibody, Hnf6 antibody, Hnf6b antibody, OC-1 antibody, Oc1 antibody, onecut antibody, onecut1 antibody, id:ibd5005 antibody, HNF6 antibody, HNF6A antibody, HNF-6a antibody, oc1 antibody, onecut1l antibody, zgc:65904 antibody, zgc:77450 antibody, one cut domain, family member 1 antibody, one cut homeobox 1 antibody, one cut domain, family member, like antibody, Onecut1 antibody, onecutl antibody, ONECUT1 antibody, onecut1 antibody

Background: One cut homeobox 1 (ONECUT1), also called Hepatocyte nuclear factor 6 (HNF6) is found strong expression in liver and lower expression in testis and skin. The gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer.

UniProt: Q9UBC0