RAB3A antibody (AA 192-220)

Catalog No. ABIN3032423

Product Details anti-RAB3A Antibody

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Binding Specificity: AA 192-220

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB3A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: Amino acids 192-220 (DTADPAVTGAKQGPQLSDQQVPPHQDCAC-human) were used as the immunogen for this Rab3A antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the Rab3A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Rab3A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for RAB3A

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Alternative Name: Rab3A (RAB3A Products)

Synonyms: RAB3 antibody, rab3a antibody, zgc:92276 antibody, RAB3A antibody, rab-3a antibody, si:ch211-255d18.4 antibody, zgc:112516 antibody, RAB3A, member RAS oncogene family antibody, RAB3A, member RAS oncogene family, a antibody, RAB3A, member RAS oncogene family L homeolog antibody, RAB3A, member RAS oncogene family, b antibody, RAB3A antibody, Rab3a antibody, rab3aa antibody, rab3a.L antibody, rab3a antibody, rab3ab antibody

Background: Ras-related protein Rab-3A is a protein that in humans is encoded by the RAB3A gene. Synapsin I stimulated the Rab3A cycle by increasing GTP binding, GTPase activity, and Rab3A recruitment to the synaptic vesicle membrane. Conversely, Rab3A inhibited Synapsin I binding to actin and Synapsin I-induced synaptic vesicle clustering. It has been found that the protein is necessary for both forms of synaptic plasticity, and it is also involved in calcium exocytosis in neurons. In addition to that, Rab3A has been found to regulate a late step in synaptic vesicle fusion.

Gene ID: 5864

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport