TMED10 antibody (C-Term)

Catalog No. ABIN303302

The Rabbit Polyclonal anti-TMED10 antibody is suitable to detect TMED10 in samples from Human, Mouse and Rat. It has been validated for WB and IHC (p).

Quick Overview for TMED10 antibody (C-Term) (ABIN303302)

Target: TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMED10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TMED10 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to a 19 amino acid peptide from near the carboxy terminus of human TMP21.

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Purified

Immunogen: Synthetic Peptide corresponding to 19 amino acid peptide from near the carboxy terminus of human TMP21.

Application Details

Application Notes: Immunohistochemistry on Paraffin Sections (3 μg/mL). Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for TMED10

Target: TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

Alternative Name: TMED10 / TMP21

Background: TMP21 is a integral membrane protein that is localized in microsomal membranes, zymogen granule membrane and the plasma membrane. It is ubiquitously expressed and is involved in vesicular targeting and protein transport. Recent studies have shown that TMP21 is a component of presenillin complexes and differentially regulates gamma-secretase cleavage of the amyloid precursor protein, without affecting epsilon-secretase activity.Synonyms: 21 kDa transmembrane-trafficking protein, S31I125, Transmembrane emp24 domain-containing protein 10, Transmembrane protein Tmp21

Gene ID: 10972

NCBI Accession: NP_006818

UniProt: P49755