PLAU antibody

Catalog No. ABIN303620

The Mouse Monoclonal anti-PLAU antibody is suitable to detect PLAU in samples from Human. It has been validated for WB, EIA, IHC (fro) and Func.

Quick Overview for PLAU antibody (ABIN303620)

Target: PLAU (Plasminogen Activator, Urokinase (PLAU))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PLAU antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: PGM2001

Product Details anti-PLAU Antibody

Specificity: Binds to human high molecular weight single-chain urokinase type plasminogen activator (HMW-scuPA, 54 kDa), to high molecular weight two-chain urokinase type plasminogen activator (HMW-tcuPA, 52 kDa) and to low molecular weight single-chain urokinase type plasminogen activator (LMW-scuPA, 33kDa) with high affinity (Kd = 0.1 nM) and does inhibit the ability of urokinase to activate plasminogen. Urokinase reaction with synthetic substrate S2444 is not inhibited. Highly specific for urokinase, no cross-reactions were found with other serine proteases (tissue plasminogen activator, plasmin, trypsin, chymotrypsin, elastase, and thrombin). Human plasma or plasma proteins do not interfere with its binding to urokinase.

Purification: Precipitation by PEG-6000 and DEAE-cellulose chromatography (gradient)

Immunogen: Urokinase

Isotype: IgG1

Application Details

Application Notes: Use 1 ml sterile pure water

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilised from solution containing 0.2 mg antibody, 1% mannitol, 0.15 M sodium chloride, 0.01 M sodium phosphate. Azide-free

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PLAU

Target: PLAU (Plasminogen Activator, Urokinase (PLAU))

Alternative Name: Urokinase

Background: Mouse anti-human urokinase monoclonal antibody, Unconjugated, Clone PGM2001

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration