FMO1 antibody (C-Term)

Catalog No. ABIN3042396

The Rabbit Polyclonal anti-FMO1 antibody (ABIN3042396) specifically detects FMO1 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FMO1 antibody (C-Term) (ABIN3042396)

Target: FMO1 (Flavin Containing Monooxygenase 1 (FMO1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FMO1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FMO1 Antibody

Binding Specificity: C-Term

Purpose: Anti-FMO1 Antibody

Sequence: AFPFLDESVV KVEDGQASLY KYIFPAHLQK

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by one amino acid,and from the related rat sequence by two amino acids.

Characteristics: Anti-FMO1 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human FMO1, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FMO1

Target: FMO1 (Flavin Containing Monooxygenase 1 (FMO1))

Alternative Name: FMO1

Background:

Background: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: flavin containing dimethylaniline monoxygenase 1

Sequence Similarities: Belongs to the FMO family.

Molecular Weight: 60 kDa

Gene ID: 2326

UniProt: Q01740