ING1 antibody (Middle Region)

Catalog No. ABIN3042467

The Rabbit Polyclonal anti-ING1 antibody is suitable to detect ING1 in samples from Human. It has been validated for WB.

Quick Overview for ING1 antibody (Middle Region) (ABIN3042467)

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ING1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ING1 Antibody

Binding Specificity: Middle Region

Purpose: Anti-ING1 Antibody

Sequence: KELDECYERF SRETDGAQKR RMLHCVQRAL IR

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by seven amino acids.

Characteristics: Anti-ING1 Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ING1, different from the related mouse sequence by seven amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ING1

Target: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Alternative Name: ING1

Background:

Background: Inhibitor of growth protein 1 is a protein that in humans is encoded by the ING1 gene. It is mapped to 13q34. This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene Full Name: inhibitor of growth family member 1

Sequence Similarities: Contains 1 HMG box DNA-binding domain.

Molecular Weight: 47 kDa

Gene ID: 3621

UniProt: Q9UK53

Pathways: Protein targeting to Nucleus, Autophagy