KAT2A antibody (N-Term)

Catalog No. ABIN3042472

This Rabbit Polyclonal antibody specifically detects KAT2A in WB. It exhibits reactivity toward Human.

Quick Overview for KAT2A antibody (N-Term) (ABIN3042472)

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KAT2A Antibody

Binding Specificity: AA 75-106, N-Term

Purpose: Anti-KAT2A/GCN5 Antibody

Sequence: DPARPGLSQQ QRASQRKAQV RGLPRAKKLE KL

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-KAT2A/GCN5 Antibody (ABIN3042472). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human KAT2A/GCN5, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for KAT2A

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Alternative Name: KAT2A

Background:

Synonyms: Histone acetyltransferase KAT2A,2.3.1.48,General control of amino acid synthesis protein 5-like 2,Histone acetyltransferase GCN5,HsGCN5,Lysine acetyltransferase 2A,STAF97,KAT2A,GCN5, GCN5L2, HGCN5,

Tissue Specificity: Expressed in all tissues tested, with most abundant expression in ovary.

Background: Histone acetyltransferase KAT2A?is an?enzyme?that in humans is encoded by the?KAT2A?gene. It is mapped to 17q21. KAT2A, or GCN5, GCN5L2, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. The GCN5 protein, a regulator of transcription activation in yeast, promotes maximal levels of transcription by 2 transcriptional activators, GCN4 and the HAP2-HAP3-HAP4 complex.?The GCN4 protein activates transcription of a large number of amino acid biosynthetic genes under limiting amino acid conditions and the HAP2-HAP3-HAP4 complex is thought to mediate transcription of genes involved in respiratory functions.?GCN5 also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner.

Molecular Weight: 94 kDa

Gene ID: 2648

UniProt: Q92830

Pathways: Chromatin Binding, Tube Formation