Serotonin Receptor 2B antibody (C-Term)

Catalog No. ABIN3042730

Product Details anti-Serotonin Receptor 2B Antibody

Target: Serotonin Receptor 2B (HTR2B)

Binding Specificity: AA 446-478, C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 2B antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for 5-hydroxytryptamine receptor 2B(HTR2B) detection. Tested with WB in Human,Rat.

Sequence: MRLRSSTIQS SSIILLDTLL LTENEGDKTE EQ

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for 5-hydroxytryptamine receptor 2B(HTR2B) detection. Tested with WB in Human,Rat.
Gene Name: 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
Protein Name: 5-hydroxytryptamine receptor 2B

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT2B Receptor (446-478aa MRLRSSTIQSSSIILLDTLLLTENEGDKTEEQ V), different from the related mouse sequence by six amino acids, and from the related rat sequence by nine amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for Serotonin Receptor 2B

Target: Serotonin Receptor 2B (HTR2B)

Alternative Name: HTR2B (HTR2B Products)

Background: 5HT2B Receptor is known as HTR2B. This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.

Synonyms: 5 HT 2B antibody|5 HT 2B receptor antibody|5 HT(2B) antibody|5 HT2B antibody|5 hydroxytryptamine (serotonin) receptor 2B antibody|5 hydroxytryptamine (serotonin) receptor 2B G protein coupled antibody|5 hydroxytryptamine 2B receptor antibody|5 hydroxytryptamine receptor 2B antibody|5-HT-2B antibody|5-HT2B antibody|5-hydroxytryptamine receptor 2B antibody|5HT(2B) antibody|5HT2B_HUMAN antibody| 5HT2F antibody|Htr 2b antibody|Htr2b antibody|NP75 protein antibody|SEROTONIN 5HT2B RECEPTOR antibody|Serotonin receptor 2B antibody| Stomach fundus serotonin receptor antibody

Gene ID: 3357

UniProt: P41595

Pathways: JAK-STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process