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Serotonin Receptor 2B antibody (HTR2B) (AA 408-435) Primary Antibody

HTR2B Reactivity: Human, Mouse, Rat IHC (p), WB Host: Rabbit Polyclonal RB20470 unconjugated
Pubmed (1)
Catalog No. ABIN655076
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  • Target See all Serotonin Receptor 2B (HTR2B) Antibodies
    Serotonin Receptor 2B (HTR2B)
    Binding Specificity
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 408-435, C-Term
    Reactivity
    • 56
    • 17
    • 16
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 53
    • 3
    Rabbit
    Clonality
    • 54
    • 2
    Polyclonal
    Conjugate
    • 29
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Serotonin Receptor 2B antibody is un-conjugated
    Application
    • 23
    • 22
    • 16
    • 13
    • 12
    • 9
    • 9
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This HTR2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-435 amino acids from the C-terminal region of human HTR2B.
    Clone
    RB20470
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. WB: 1:2000. IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Li, Sun, Li, Zhai, Wang, Chen, Lu: "Chronic restraint stress reduces carbon tetrachloride-induced liver fibrosis." in: Experimental and therapeutic medicine, Vol. 11, Issue 6, pp. 2147-2152, 2016 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

  • Target
    Serotonin Receptor 2B (HTR2B)
    Alternative Name
    HTR2B (HTR2B Products)
    Synonyms
    5-HT2B, 5HT2B, 5htr2b, HTR2B, 5ht2b, zgc:194094, zgc:194119, AJ012488, AV377389, 5-HT(2B), 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled, 5-hydroxytryptamine (serotonin) receptor 2B, HTR2B, htr2b, Htr2b
    Background
    Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets, central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.
    Molecular Weight
    54298
    Gene ID
    3357
    NCBI Accession
    NP_000858
    UniProt
    P41595
    Pathways
    JAK-STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
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