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ABCA4 antibody (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4) (AA 1893-1906) Primary Antibody

ABCA4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3042922
$240.00
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100 μg
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  • Target
    ABCA4
    Binding Specificity
    AA 1893-1906, C-Term
    Reactivity
    Human
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    This ABCA4 antibody is un-conjugated
    Application
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Retinal-specific ATP-binding cassette transporter(ABCA4) detection. Tested with WB in Human.
    Sequence
    TLLVQRHFFL SQWI
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Retinal-specific ATP-binding cassette transporter(ABCA4) detection. Tested with WB in Human.
    Gene Name: ATP-binding cassette, sub-family A(ABC1), member 4
    Protein Name: Retinal-specific ATP-binding cassette transporter
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human ABCA4(1893-1906aa TLLVQRHFFLSQWI).
    Isotype
    IgG
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Precaution of Use
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Expiry Date
    12 months
  • Target
    ABCA4
    Alternative Name
    ABCA4 (ABCA4 Antibody Abstract)
    Synonyms
    ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1, AW050280, Abc10, Abcr, D430003I15Rik, RmP, abcr, ffm, rmp, rp19, stgd, abc10, armd2, cord3, stgd1, zgc:91823, ATP binding cassette subfamily A member 4, ATP-binding cassette, sub-family A (ABC1), member 4, ATP binding cassette subfamily A member 4 L homeolog, ATP-binding cassette, sub-family A (ABC1), member 4a, ABCA4, Abca4, abca4, abca4.L, abca4a
    Background
    ABCA4(ATP-Binding Cassette, Subfamily A, Member 4), also known as ABCR, is a protein which in humans is encoded by the ABCA4 gene. ABCA4 is a member of the ATP-binding cassette transporter gene sub-family A(ABC1) found exclusively in multicellular eukaryotes. Using a whole genome radiation hybrid panel, Allikmets et al.(1997) mapped the ABCR gene to 1p21-p13. Allikmets et al.(1997) localized ABCR transcripts exclusively within photoreceptor cells, indicating that ABCR mediates the transport of an essential molecule(or ion) either into or out of photoreceptor cells. Molday et al.(2000) showed by immunofluorescence microscopy and Western blot analysis that ABCR is present in foveal and peripheral cone, as well as rod, photoreceptors. The results suggested that the loss in central vision experienced by patients with Stargardt macular dystrophy arises directly from ABCR-mediated foveal cone degeneration.

    Synonyms: ABC 10 antibody|ABC A4 antibody|ABC10 antibody|ABCA 4 antibody|abcA4 antibody|ABCA4_HUMAN antibody|ABCR antibody|ARMD 2 antibody|ARMD2 antibody|ATP binding cassette 10 antibody|ATP binding cassette sub family A member 4 antibody|ATP binding cassette sub family A member4 antibody|ATP binding cassette transporter antibody|ATP binding cassette transporter retinal specific antibody|ATP binding cassette, sub family A(ABC1), member 4 antibody|ATP binding cassette, sub family A(ABC1), member4 antibody|ATP binding cassette10 antibody|ATP binding transporter, retina specific antibody|ATP-binding cassette sub-family A member 4 antibody|CORD 3 antibody|CORD3 antibody|DKFZp781N1972 antibody|FFM antibody|FLJ17534 antibody|Photoreceptor rim protein antibody|Retina specific ABC transporter antibody|Retinal specific ATP binding cassette transporter antibody|Retinal-specific ATP-binding cassette transporter antibody|RIM ABC transporter antibody|RIM protein antibody|RmP antibody|RP 19 antibody|RP19 antibody|Stargardt disease protein antibody|STGD antibody|STGD1 antibody
    UniProt
    P78363
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