CRP antibody (C-Term)

Catalog No. ABIN3043017

This anti-CRP antibody is a Rabbit Polyclonal antibody detecting CRP in WB. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for CRP antibody (C-Term) (ABIN3043017)

Target: CRP (C-Reactive Protein (CRP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRP Antibody

Binding Specificity: AA 209-224, C-Term

Purpose: Anti-C Reactive Protein/CRP Antibody Picoband®

Sequence: KYEVQGEVFT KPQLWP

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-C Reactive Protein/CRP Antibody (ABIN3043017). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human C Reactive Protein.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
1. Kilpatrick, J. M., Volanakis, J. E. : Molecular genetics, structure, and function of C-reactive protein. Immun. Res. 10: 43-53, 1991. 2. Kuta, A. E., Baum, L. L. : C-reactive protein is produced by a small number of normal human peripheral blood lymphocytes. J. Exp. Med. 164: 321-326, 1986. 3. Oliveira, E. B., Gotshlich, E. C., Liu, T. : Primary structure of human C-reactive protein. J. Biol. Chem. 254: 489-502, 1979.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

References for anti-CRP antibody (ABIN3043017)

Shi, Song, Zhang, Li, Li: "Correlation between the microinflammatory state and left ventricular structural and functional changes in maintenance haemodialysis patients." in: Experimental and therapeutic medicine, Vol. 6, Issue 2, pp. 532-536, (2013) (PubMed).

Target Details for CRP

Target: CRP (C-Reactive Protein (CRP))

Alternative Name: CRP

Background:

Synonyms: C-reactive protein,C-reactive protein (1-205),CRP,PTX1,

Tissue Specificity: Found in plasma.

Background: C Reactive Protein (CRP) is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is composed of 5 identical, 21,500-molecular weight subunits. CRP mediates activities associated with preimmune nonspecific host resistance. CRP shows the strongest association with cardiovascular events. It is detectable on the surface of about 4 % of normal peripheral blood lymphocytes. Acute phase reactant CRP is produced in the liver.

Sequence Similarities: Belongs to the pentaxin family.

Molecular Weight: 43 kDa

UniProt: P02741

Pathways: Carbohydrate Homeostasis