Kallikrein 11 antibody (C-Term)

Catalog No. ABIN3043137

Product Details anti-Kallikrein 11 Antibody

Target: Kallikrein 11 (KLK11)

Binding Specificity: AA 233-250, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Kallikrein-11(KLK11) detection. Tested with WB, IHC-P in Human.

Sequence: YTKVCKYVDW IQETMKNN

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Kallikrein-11(KLK11) detection. Tested with WB, IHC-P in Human.
Gene Name: kallikrein-related peptidase 11
Protein Name: Kallikrein-11(hK11)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 11(233-250aa YTKVCKYVDWIQETMKNN).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

References for anti-Kallikrein 11 antibody (ABIN3043137)

Gao, Wang, Yan, Zeng, Ma, Niu, Zhou, Jiang, Chen: "Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats." in: PLoS ONE, Vol. 11, Issue 3, pp. e0151118, (2016) (PubMed).

Target Details for Kallikrein 11

Target: Kallikrein 11 (KLK11)

Alternative Name: KLK11 (KLK11 Products)

Synonyms: KLK11 antibody, 2310015I08Rik antibody, Prss20 antibody, TLSP antibody, PRSS20 antibody, kallikrein related peptidase 11 antibody, kallikrein related-peptidase 11 antibody, kallikrein-related peptidase 11 antibody, KLK11 antibody, Klk11 antibody

Background: KLK11(KALLIKREIN 11), also called PRSS20 or TLSP, is a protein that in humans is encoded by the KLK11 gene. KLK11 is a member of the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. The KLK11 gene is mapped to 19q13.41. The KLK11 gene contains 6 exons, the first of which is noncoding. KLK11 shares 48 % amino acid sequence identity with mouse neuropsin, 43 % identity with both human trypsin-1 and human kallikrein, and 38 % identity with the mouse nerve growth factor gamma subunit. Alternate splicing of the KLK11 gene results in two transcript variants encoding two different isoforms which are differentially expressed. Western blot analysis of recombinant KLK11 suggested that the protein is secreted and posttranslationally processed.

Synonyms: Hippostasin antibody|hK11 antibody|Kallikrein 11 antibody|Kallikrein 11 isoform 1 preproprotein antibody|Kallikrein 11 isoform 2 precursor antibody|Kallikrein 11 precursor antibody|Kallikrein related peptidase 11 antibody|Kallikrein-11 inactive chain 2 antibody|KLK 11 antibody|Klk11 antibody|KLK11_HUMAN antibody|MGC33060 antibody|Protease serine 20 trypsin like antibody|Protease serine trypsin like antibody|PRSS20 antibody|Serine protease 20 antibody|TLSP antibody|Trypsin like protease antibody|Trypsin-like protease antibody

Pathways: Complement System