Annexin A3 antibody (Middle Region)

Catalog No. ABIN3043176

The Rabbit Polyclonal anti-Annexin A3 antibody (ABIN3043176) specifically detects Annexin A3 in WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Annexin A3 antibody (Middle Region) (ABIN3043176)

Target: Annexin A3 (ANXA3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Annexin A3 Antibody

Binding Specificity: AA 124-141, Middle Region

Purpose: Anti-Annexin A3/ANXA3 Antibody

Sequence: RQMKEISQAY YTAYKKNL

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Annexin A3/ANXA3 Antibody (ABIN3043176). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of rat Annexin A3, different from the related human and mouse sequences by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.01 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Annexin A3

Target: Annexin A3 (ANXA3)

Alternative Name: ANXA3

Background:

Synonyms: Annexin A3,35-alpha calcimedin,Annexin III,Annexin-3,Lipocortin III,Placental anticoagulant protein III,PAP-III,Anxa3,Anx3,

Tissue Specificity: Pancreas and other tissues and body fluids (indicating it may have other physiological functions besides its role in digestion).

Background: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

Sequence Similarities: Belongs to the annexin family.

Molecular Weight: 36 kDa

UniProt: P14669