Annexin A3 antibody (Middle Region)

Catalog No. ABIN3043501

Product Details anti-Annexin A3 Antibody

Target: Annexin A3 (ANXA3)

Binding Specificity: AA 153-184, Middle Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purpose: Rabbit IgG polyclonal antibody for Annexin A3(ANXA3) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.

Sequence: RKALLTLADG RRDESLKVDE HLAKQDAQIL YK

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Annexin A3(ANXA3) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.
Gene Name: annexin A3
Protein Name: Annexin A3

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Annexin A3 (153-184aa RKALLTLADGRRDESLKVDEHLAKQDAQILYK), different from the related mouse sequence by one amino acid, and from the related rat sequence by three amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for Annexin A3

Target: Annexin A3 (ANXA3)

Alternative Name: ANXA3 (ANXA3 Products)

Synonyms: MGC80326 antibody, anxa3 antibody, zgc:101718 antibody, ANXA3 antibody, ANX3 antibody, Anx3 antibody, LC3 antibody, LRRGT00047 antibody, annexin A3 L homeolog antibody, annexin A3a antibody, annexin A3 antibody, Annexin A3 antibody, anxa3.L antibody, anxa3a antibody, ANXA3 antibody, anxa3 antibody, Anxa3 antibody

Background: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

Synonyms: 2-cyclic phosphate 2-phosphohydrolase antibody|35-alpha calcimedin antibody|Annexin A3 antibody|Annexin III antibody|Annexin-3 antibody|ANX3 antibody|ANXA 3 antibody|Anxa3 antibody|ANXA3_HUMAN antibody|Inositol 1 2 cyclic phosphate 2 phosphohydrolase antibody| Inositol 1 antibody|Lipocortin III antibody|OTTHUMP00000160701 antibody| OTTHUMP00000219237 antibody|OTTHUMP00000219238 antibody|PAP III antibody|PAP-III antibody| Placental anticoagulant protein III antibody

Gene ID: 306

UniProt: P12429