Resistin antibody (C-Term)

Catalog No. ABIN3043196

The Rabbit Polyclonal anti-Resistin antibody is suitable to detect Resistin in samples from Mouse. It has been validated for WB and IHC.

Quick Overview for Resistin antibody (C-Term) (ABIN3043196)

Target: Resistin (RETN)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Resistin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Resistin Antibody

Binding Specificity: AA 93-114, C-Term

Purpose: Anti-Resistin/RETN Antibody

Sequence: CHCQCARIDW TAARCCKLQV AS

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Resistin/RETN Antibody (ABIN3043196). Tested in IHC, WB applications. This antibody reacts with Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Resistin.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse
Western blot, 0.1-0.5 μg/mL, Mouse

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Resistin

Target: Resistin (RETN)

Alternative Name: RETN

Background:

Synonyms: Resistin,Adipose tissue-specific secretory factor,ADSF,Adipose-specific cysteine-rich secreted protein A12-alpha,Cysteine-rich secreted protein FIZZ3,Retn,Fizz3,

Tissue Specificity: Expressed in white but not brown adipose tissue in a variety of organs.

Background: Resistin, also known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) is a cysteine-rich protein that in humans is encoded by the RETN gene. The resistin gene comprises 4 exons, the first of which is untranslated, and spans approximately 1,750 bp. The human resistin gene is localized to a cloned fragment of human chromosome 19. In primates, pigs and dogs, resistin is secreted by immune and epithelial cells while in rodents, it is secreted by adipose tissue. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus.

Sequence Similarities: Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.

Molecular Weight: 38 kDa

UniProt: Q99P87

Pathways: Feeding Behaviour, Smooth Muscle Cell Migration