Caspase 6 antibody (N-Term)

Catalog No. ABIN3043219

The Rabbit Polyclonal anti-Caspase 6 antibody (ABIN3043219) specifically detects Caspase 6 in WB, IHC and FACS. The antibody is reactive with Human samples.

Quick Overview for Caspase 6 antibody (N-Term) (ABIN3043219)

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-Caspase 6 Antibody

Binding Specificity: AA 24-44, N-Term

Purpose: Anti-Caspase-6(P18)/CASP6 Antibody

Sequence: AFYKREMFDP AEKYKMDHRR R

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Caspase-6 (P18)/CASP6 Antibody (ABIN3043219). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Caspase-6(P18).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Alternative Name: CASP6

Background:

Synonyms: Caspase-6,CASP-6,3.4.22.59,Apoptotic protease Mch-2,Caspase-6 subunit p18,Caspase-6 subunit p11,CASP6,MCH2,

Tissue Specificity: High level expression seen in spleen and lung, low level expression seen in brain, heart, liver, kidney, testis and skeletal muscle.

Background: Caspase 6 is an enzyme that in humans is encoded by the caspase 6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Using radiation hybrid mapping, the Caspase 6 gene is localized to human chromosome 4q25-q26. Caspase 6 functions as a downstream enzyme in the caspase activation cascade. And Caspase 6 can cleave lamin A to its signature apoptotic fragment.

Sequence Similarities: Belongs to the peptidase C14A family.

Molecular Weight: 35 kDa

UniProt: P55212

Pathways: Apoptosis, Caspase Cascade in Apoptosis