IL16 antibody (AA 1212-1332)

Catalog No. ABIN3043243

This Rabbit Polyclonal antibody specifically detects IL16 in WB, ELISA, IHC and ICC. It exhibits reactivity toward Human.

Quick Overview for IL16 antibody (AA 1212-1332) (ABIN3043243)

Target: IL16 (Interleukin 16 (IL16))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL16 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Product Details anti-IL16 Antibody

Binding Specificity: AA 1212-1332

Purpose: Anti-IL16 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-IL16 Antibody Picoband® (ABIN3043243). Tested in ELISA, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human IL-16 recombinant protein (Position: S1212-S1332). Human IL-16 shares 86% amino acid (aa) sequence identity with mouse IL-16.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry , 0.5-1 μg/mL, Human, -
Western blot, 0.1-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cruikshank W, Center DM (1982). "Modulation of lymphocyte migration by human lymphokines. II. Purification of a lymphotactic factor (LCF)".J. Immunol. 128 (6): 2569-74 2. Drwinga, H. L., Toji, L. H., Kim, C. H., Greene, A. E., Mulivor, R. A. NIGMS human/rodent somatic cell hybrid mapping panels 1 and 2. Genomics 16: 311-314, 1993. 3. Bannert, N., Kurth, R., Baier, M. The gene encoding mouse interleukin-16 consists of seven exons and maps to Chromosome 7 D2-D3. Immunogenetics 49: 704-706, 1999. 4. Hudson, T. J., Stein, L. D., Gerety, S. S., Ma, J., Castle, A. B., Silva, J., Slonim, D. K., Baptista, R., Kruglyak, L., Xu, S. H., Hu, X., Colbert, A. M. E., and 39 others. An STS-based map of the human genome. Science 270: 1945-1954, 1995.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for IL16

Target: IL16 (Interleukin 16 (IL16))

Alternative Name: IL16

Background:

Synonyms: Pro-interleukin-16,Interleukin-16,IL-16,Lymphocyte chemoattractant factor,LCF,IL16,

Tissue Specificity: Isoform 3 is expressed in hemopoietic tissues, such as resting T-cells, but is undetectable during active T-cell proliferation.

Background: Interleukin 16 (IL-16) is a cytokine that released by a variety of cells (including lymphocytes and some epithelial cells) that has been characterized as a chemoattractant for certain immune cells expressing the cell surface molecule CD4. It is mapped to 15q25.1. IL-16 was originally described as a factor that could attract activated T cells in humans. It was previously called lymphocyte chemoattractant factor (LCF), and the augmentation of IL16 stimulation by CCR5 plays a role in regulation of Th1 cell recruitment and activation at sites of inflammation.

Sequence Similarities: Contains 4 PDZ (DHR) domains.

Molecular Weight: 45-55 kDa

Gene ID: 3603

UniProt: Q14005