KIAA1524 antibody (C-Term)

Catalog No. ABIN3043277

Product Details anti-KIAA1524 Antibody

Target: KIAA1524

Binding Specificity: AA 854-889, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIAA1524 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Protein CIP2A(KIAA1524) detection. Tested with WB in Human,Mouse.

Sequence: EVQKAQLEGR LEEKESLVKL QQEELNKHSH MIAMIH

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Protein CIP2A(KIAA1524) detection. Tested with WB in Human,Mouse.
Gene Name: KIAA1524
Protein Name: Protein CIP2A

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human KIAA1524 (854-889aa EVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIH), different from the related mouse sequence by three amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for KIAA1524

Target: KIAA1524

Alternative Name: KIAA1524 (KIAA1524 Products)

Synonyms: CIP2A antibody, p90 antibody, AA408511 antibody, AU018569 antibody, Cip2a antibody, Kiaa1524 antibody, KIAA1524 antibody, LOC100222895 antibody, RGD1310335 antibody, cell proliferation regulating inhibitor of protein phosphatase 2A antibody, RIKEN cDNA C330027C09 gene antibody, KIAA1524 antibody, cell proliferation regulating inhibitor of protein phosphatase 2A L homeolog antibody, CONSTANS interacting protein 2a antibody, CIP2A antibody, C330027C09Rik antibody, KIAA1524 antibody, cip2a.L antibody, CIP2a antibody, cip2a antibody, Cip2a antibody

Background: Protein CIP2A, also known as cancerous inhibitor of PP2A (CIP2A), is a protein that in humans is encoded by the KIAA1524 gene. CIP2A is required for the malignant cellular growth and for in vivo tumor formation. In accordance with the oncogenic role of CIP2A, overexpression of CIP2A promotes Ras-elicited cell growth and transforms immortalized human cells (HEK-TERVs). More recently CIP2A has been shown to regulate phosphorylation and activity of many other oncoproteins and to drive malignant cell growth and tumorigenesis in various human cancer types. Importantly, CIP2A deficient mice are viable, suggesting that targeting of oncogenic function of CIP2A would not result in serious side-effects.

Synonyms: Cancerous inhibitor of PP2A antibody|Cancerous Inhibitor of Protein Phosphatase 2A antibody|CIP2A antibody|CIP2A_HUMAN antibody| FLJ12850 antibody|Kiaa1524 antibody|MGC163436 antibody|p90 antibody|p90 autoantigen antibody|Protein CIP2A antibody

Gene ID: 57650