STRAP antibody (N-Term)
Quick Overview for STRAP antibody (N-Term) (ABIN3043302)
Target
See all STRAP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Purpose
- Anti-Unrip/STRAP Antibody
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Sequence
- AADFTAKVWD AVSGDELMTL AHKHIVK
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Specificity
- No cross reactivity with other proteins.
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Predicted Reactivity
- identical to the related mouse,rat sequences.
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Characteristics
- Anti-Unrip/STRAP Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human Unrip, identical to the related mouse and rat sequences.
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Isotype
- IgG
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Application Notes
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, HumanWestern blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Expiry Date
- 12 months
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- STRAP (Serine/threonine Kinase Receptor Associated Protein (STRAP))
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Alternative Name
- STRAP
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Background
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Background: Unrip is also known as STRAP (Serine-threonine kinase receptor-associated protein). It is anenzyme that in humans is encoded by the STRAP gene. It is mapped to 12p12.3. UNRIP is integrated into a complex with UNR or with the SMN complex in vivo in a mutually exclusive manner. It is concluded that UNRIP is the first component of the uridine-rich snRNP assembly machinery that associates with the SMN complex in a compartment-specific way, and it may play a crucial role in the intracellular distribution of the SMN complex.
Gene Full Name: serine/threonine kinase receptor associated protein
Sequence Similarities: Belongs to the WD repeat STRAP family.
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Molecular Weight
- 39 kDa
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Gene ID
- 11171
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UniProt
- Q9Y3F4
Target
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