L-Selectin antibody (AA 39-372)
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- Target See all L-Selectin (SELL) Antibodies
- L-Selectin (SELL) (Selectin L (SELL))
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Binding Specificity
- AA 39-372
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This L-Selectin antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for L-selectin(SELL) detection. Tested with WB, IHC-P, ELISA in Human,Mouse,Rat.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for L-selectin(SELL) detection. Tested with WB, IHC-P, ELISA in Human,Mouse,Rat.
Gene Name: selectin L
Protein Name: L-selectin - Purification
- Immunogen affinity purified.
- Immunogen
- E. coli-derived human L-selectin recombinant protein (Position: W39-Y372). Human L-selectin shares 77.5 % and 78.7 % amino acid (aa) sequence identity with mouse and rat L-selectin, respectively.
- Isotype
- IgG
- Top Product
- Discover our top product SELL Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat , The detection limit for L-selectin is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- L-Selectin (SELL) (Selectin L (SELL))
- Alternative Name
- SELL (SELL Products)
- Synonyms
- CD62L antibody, LAM1 antibody, LECAM1 antibody, LEU8 antibody, LNHR antibody, LSEL antibody, LYAM1 antibody, PLNHR antibody, TQ1 antibody, A.11 antibody, L-selectin antibody, LECAM-1 antibody, SELE antibody, AI528707 antibody, Lnhr antibody, Ly-22 antibody, Ly-m22 antibody, Lyam-1 antibody, Lyam1 antibody, selectin L antibody, selectin, lymphocyte antibody, SELL antibody, Sell antibody
- Target Type
- Chemical
- Background
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CD62L, also known as L-selectin, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.
Synonyms: A.11 antibody|AI528707 antibody|CD62 antigen ligand antibody|CD62 antigen-like family member L antibody|CD62L antibody|gp90 MEL antibody|gp90-MEL antibody|hLHRc antibody|IgA nephropathy, susceptibility to, included antibody|L Selectin antibody|L-selectin antibody|LAM-1 antibody|LAM1 antibody|LECAM1 antibody|LEU8 antibody|Leukocyte adhesion molecule 1 antibody|Leukocyte surface antigen Leu-8 antibody|Leukocyte surface antigen Leu8 antibody|Leukocyte-endothelial cell adhesion molecule 1 antibody|LNHR antibody|LSEL antibody|Ly-22 antibody|Ly-m22 antibody|Lyam-1 antibody|LYAM1 antibody|LYAM1_HUMAN antibody|Lymph node homing receptor antibody|Lymphocyte adhesion molecule 1 antibody|Lymphocyte antigen 22 antibody|Lymphocyte surface MEL-14 antigen antibody|MEL-14 antibody|Pln homing receptor antibody|PLNHR antibody|Selectin L antibody|Selectin, lymphocyte antibody|SELL antibody|TQ1 antibody - Gene ID
- 6402
- UniProt
- P14151
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