SOX5 antibody (C-Term)

Catalog No. ABIN3043348

Product Details anti-SOX5 Antibody

Target: SOX5 (SRY (Sex Determining Region Y)-Box 5 (SOX5))

Binding Specificity: AA 495-528, C-Term

Reactivity: Human, Rat, Mouse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX5 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Anti-SOX5 Antibody Picoband®

Sequence: EKEKTTLESL TQQLAVKQNE EGKFSHAMMD FNLS

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-SOX5 Antibody Picoband® (ABIN3043348). Tested in WB applications. This antibody reacts with Human, Mouse, Pig, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SOX5, different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat, Pig
1. "Entrez Gene: SOX5 SRY (sex determining region Y)-box 5". 2. Ikeda T, Zhang J, Chano T et al. (2003). "Identification and characterization of the human long form of Sox5 (L-SOX5) gene". Gene 298 (1): 59-68. 3. Wunderle VM, Critcher R, Ashworth A, Goodfellow PN (Jan 1997). "Cloning and characterization of SOX5, a new member of the human SOX gene family". Genomics 36 (2): 354-8.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for SOX5

Target: SOX5 (SRY (Sex Determining Region Y)-Box 5 (SOX5))

Alternative Name: SOX5 (SOX5 Products)

Background:

Synonyms: Transcription factor SOX-5,SOX5,

Tissue Specificity: Placenta, liver, and to a much smaller extent, in lung.

Background: Transcription factor SOX-5 is a protein that in humans is encoded by the SOX5 gene. It is located on 12p12.1. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. In addition, the encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Sequence Similarities: Contains 1 HMG box DNA-binding domain.

Molecular Weight: 84 kDa

Gene ID: 6660

UniProt: P35711