RAB18 antibody (C-Term)

Catalog No. ABIN3043365

This anti-RAB18 antibody is a Rabbit Polyclonal antibody detecting RAB18 in WB. Suitable for Human, Rat.

Quick Overview for RAB18 antibody (C-Term) (ABIN3043365)

Target: RAB18 (RAB18, Member RAS Oncogene Family (RAB18))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB18 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAB18 Antibody

Binding Specificity: AA 156-192, C-Term

Purpose: Anti-Rab18 Antibody Picoband®

Sequence: DGVQCAFEEL VEKIIQTPGL WESENQNKGV KLSHREE

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Rab18 Antibody Picoband® (ABIN3043365). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Rab18, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: RAB18 RAB18, member RAS oncogene family". 2. Lütcke A, Parton RG, Murphy C, Olkkonen VM, Dupree P, Valencia A, Simons K, Zerial M (December 1994). "Cloning and subcellular localization of novel rab proteins reveals polarized and cell type-specific expression". J. Cell. Sci. 107 (12): 3437-48. 3. Schafer U, Seibold S, Schneider A, Neugebauer E (Feb 2000). "Isolation and characterisation of the human rab18 gene after stimulation of endothelial cells with histamine". FEBS Lett 466 (1): 148-54.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for RAB18

Target: RAB18 (RAB18, Member RAS Oncogene Family (RAB18))

Alternative Name: RAB18

Background:

Synonyms: Ras-related protein Rab-18,RAB18,

Tissue Specificity: Ubiquitous.

Background: Ras-related protein Rab-18 is a protein that in humans is encoded by the RAB18 gene. It is a ubiquitously expressed protein with particularly high expression in the brain. The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies in zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 23 kDa

Gene ID: 22931

Pathways: SARS-CoV-2 Protein Interactome