OMG antibody (N-Term)

Catalog No. ABIN3043375

Product Details anti-OMG Antibody

Target: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Binding Specificity: AA 64-99, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OMG antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Oligodendrocyte-myelin glycoprotein(OMG) detection. Tested with WB in Human,Mouse,Rat.

Sequence: YNHFTDLHNQ LTQYTNLRTL DISNNRLESL PAHLPR

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Oligodendrocyte-myelin glycoprotein(OMG) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: oligodendrocyte myelin glycoprotein
Protein Name: Oligodendrocyte-myelin glycoprotein

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human OMG (64-99aa YNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPR), different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for OMG

Target: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Alternative Name: OMG (OMG Products)

Synonyms: OMGP antibody, omgp antibody, MGC107958 antibody, OMG antibody, DKFZp459F1351 antibody, oligodendrocyte myelin glycoprotein antibody, myelin oligodendrocyte glycoprotein antibody, oligodendrocyte-myelin glycoprotein antibody, OMG antibody, MOG antibody, Omg antibody, omg antibody

Background: Oligodendrocyte-myelin glycoprotein is a protein that in humans is encoded by the OMG gene. This gene is mapped to 17q11-q12. OMG, like neurofibromin (NF1), has growth suppressive effects and downregulates mitogenic signaling pathways closely related to those influenced by neurofibromin. Overexpression of OMG alters mitogenic signaling in fibroblasts. Cells overexpressing OMG grow more slowly in serum compared to controls and show a partial G1 block upon cell cycle analysis.

Synonyms: Oligodendrocyte-myelin glycoprotein antibody|Omg antibody|OMGP antibody|OMGP_HUMAN antibody

Gene ID: 4974

UniProt: P23515

Pathways: Neurotrophin Signaling Pathway, Regulation of Cell Size