PLD1 antibody (AA 1-330)

Catalog No. ABIN3043383

Product Details anti-PLD1 Antibody

Target: PLD1 (Phospholipase D1 (PLD1))

Binding Specificity: AA 1-330

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLD1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Phospholipase D1(PLD1) detection. Tested with WB in Human,Mouse.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Phospholipase D1(PLD1) detection. Tested with WB in Human,Mouse.
Gene Name: phospholipase D1, phosphatidylcholine-specific
Protein Name: Phospholipase D1

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PLD1 recombinant protein (Position: M1-H330). Human PLD1 shares 91.8% and 90.9% amino acid (aa) sequence identity with mouse and rat PLD1, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, The detection limit for PLD1 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for PLD1

Target: PLD1 (Phospholipase D1 (PLD1))

Alternative Name: PLD1 (PLD1 Products)

Synonyms: AA536939 antibody, C85393 antibody, Pld1a antibody, Pld1b antibody, Plda antibody, Pldb antibody, phospholipase D1 antibody, Pld1 antibody, PLD1 antibody

Background: By somatic cell hybrid analysis, PLD1 is mapped to 3q26.31. This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. And PLD1 disrupted association of gamma-secretase protein components, independent of PLD1catalytic activity. What's more, PLD1 regulates intracellular trafficking of beta-amyloid, distinct from its effect on gamma-secretase activity.

Synonyms: Choline phosphatase 1 antibody|hPLD 1 antibody|hPLD1 antibody|Human ARF activated phosphatidylcholine specific phospholipase D1a antibody|Phosphatidylcholine hydrolyzing phospholipase D1 antibody|Phosphatidylcholine-hydrolyzing phospholipase D1 antibody| Phospholipase D1 antibody|Phospholipase D1 phosphatidylcholine specific antibody| PhospholipaseD1 antibody|PL D1 antibody|PLD 1 antibody|PLD1 antibody|PLD1_HUMAN antibody

Gene ID: 5337

UniProt: Q13393