TAP2 antibody (C-Term)

Catalog No. ABIN3043415

The Rabbit Polyclonal anti-TAP2 antibody is suitable to detect TAP2 in samples from Human. It has been validated for WB.

Quick Overview for TAP2 antibody (C-Term) (ABIN3043415)

Target: TAP2 (Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TAP2 Antibody

Binding Specificity: AA 611-651, C-Term

Purpose: Anti-TAP2 Antibody

Sequence: QKQRLAIARA LVRDPRVLIL DEATSALDVQ CEQALQDWNS R

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-TAP2 Antibody (ABIN3043415). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TAP2, different from the related mouse sequence by five amino acids, and from the related rat sequence by six amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for TAP2

Target: TAP2 (Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2))

Alternative Name: TAP2

Background:

Synonyms: Antigen peptide transporter 2,APT2,ATP-binding cassette sub-family B member 3,Peptide supply factor 2,Peptide transporter PSF2,PSF-2,Peptide transporter TAP2,Peptide transporter involved in antigen processing 2,Really interesting new gene 11 protein,TAP2,ABCB3, PSF2, RING11, Y1,

Tissue Specificity: Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung. .

Background: Transporter, ATP-binding cassette, major histocompatibility complex 2 (TAP2) is a gene in humans that encodes the protein Antigen peptide transporter 2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. The gene is assigned to human chromosome 6p21.3. It is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. And this protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum.

Molecular Weight: 87 kDa

Gene ID: 6891

UniProt: Q03519

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response