SOX1 antibody (Middle Region)

Catalog No. ABIN3043439

There is 1 publication for this product available. The Rabbit Polyclonal anti-SOX1 antibody is suitable to detect SOX1 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for SOX1 antibody (Middle Region) (ABIN3043439)

Target: SOX1 (SRY (Sex Determining Region Y)-Box 1 (SOX1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SOX1 Antibody

Binding Specificity: Middle Region

Purpose: Anti-SOX1 Antibody

Sequence: QHPGAGGAHP HAHPAHPHPH HPHAHPHNPQ PMHR

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse sequence.

Characteristics: Anti-SOX1 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of Human SOX1, identical to the related mouse sequence.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-SOX1 antibody (ABIN3043439)

Yi, Xie, Liu, Wang, Xu, Liu, Li, Zhong, Peng: "Derivation and Identification of Motor Neurons from Human Urine-Derived Induced Pluripotent Stem Cells." in: Stem cells international, Vol. 2018, pp. 3628578, (2018) (PubMed).

Target Details for SOX1

Target: SOX1 (SRY (Sex Determining Region Y)-Box 1 (SOX1))

Alternative Name: SOX1

Background:

Background: SOX1 (for Sex determining region Y-box 1), located in 13q34, is a transcription factor in the Sox protein family. It means that this intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. SOX1 expression is restricted to neuroectodermin the tetrapod embryo. It is expressed particularly in the ventral striatum.

Gene Full Name: SRY-box transcription factor 1

Sequence Similarities: Belongs to the Cu-Zn superoxide dismutase family.

Molecular Weight: 39 kDa

Gene ID: 6656

UniProt: O00570