TRAP1 antibody (AA 571-704)

Catalog No. ABIN3043536

Product Details anti-TRAP1 Antibody

Target: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Binding Specificity: AA 571-704

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Heat shock protein 75 kDa, mitochondrial(TRAP1) detection. Tested with WB, IHC-P in Human,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Heat shock protein 75 kDa, mitochondrial(TRAP1) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: TNF receptor-associated protein 1
Protein Name: Heat shock protein 75 kDa, mitochondrial

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRAP1 recombinant protein (Position: A571-H704). Human TRAP1 shares 91.7% and 94% amino acid (aa) sequence identity with mouse and rat TRAP1, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for TRAP1

Target: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Alternative Name: TRAP1 (TRAP1 Products)

Synonyms: HSP 75 antibody, HSP75 antibody, HSP90L antibody, TRAP-1 antibody, 2410002K23Rik antibody, fc85a11 antibody, wu:fc85a11 antibody, TNF receptor associated protein 1 antibody, TNF receptor-associated protein 1 antibody, TRAP1 antibody, Trap1 antibody, trap1 antibody

Background: Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene. It is mapped to 16p13.3. This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. And this protein may function in regulating cellular stress responses. In addition, it was found that TRAP1 interacted with the N-terminal half of TNFR1. Also, TRAP1 interacted with the C-terminal ends of the proteins encoded by both multiple exostoses-causing genes, EXT1 and EXT2, but not with EXTL1 or EXTL3.

Synonyms: Heat shock protein 75 antibody|Heat shock protein 75 kDa antibody|Heat shock protein 75 kDa mitochondrial antibody|HSP 75 antibody|HSP 90L antibody|HSP75 antibody|HSP90L antibody|mitochondrial antibody|TNF receptor associated protein 1 antibody|TNFR associated protein 1 antibody|TNFR-associated protein 1 antibody|TRAP 1 antibody|TRAP-1 antibody|Trap1 antibody|TRAP1_HUMAN antibody|Tumor necrosis factor receptor associated protein antibody|Tumor necrosis factor type 1 receptor associated protein antibody|Tumor necrosis factor type 1 receptor-associated protein antibody

Gene ID: 10131

UniProt: Q12931