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TLR5 antibody (C-Term)

TLR5 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3043542
  • Target See all TLR5 Antibodies
    TLR5 (Toll-Like Receptor 5 (TLR5))
    Binding Specificity
    • 13
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 801-828, C-Term
    Reactivity
    • 103
    • 68
    • 34
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 94
    • 16
    • 2
    Rabbit
    Clonality
    • 87
    • 25
    Polyclonal
    Conjugate
    • 47
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR5 antibody is un-conjugated
    Application
    • 77
    • 39
    • 32
    • 14
    • 11
    • 8
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for Toll-like receptor 5(TLR5) detection. Tested with WB, IHC-P in Human.
    Sequence
    MKHQSIRGFV QKQQYLRWPE DFQDVGWF
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Toll-like receptor 5(TLR5) detection. Tested with WB, IHC-P in Human.
    Gene Name: toll-like receptor 5
    Protein Name: Toll-like receptor 5
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human TLR5 (801-828aa MKHQSIRGFVQKQQYLRWPEDFQDVGWF), different from the related mouse sequence by five amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product TLR5 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for TLR5 is approximately 0.1 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    TLR5 (Toll-Like Receptor 5 (TLR5))
    Alternative Name
    TLR5 (TLR5 Products)
    Synonyms
    SLEB1 antibody, TIL3 antibody, TLR-5 antibody, sleb1 antibody, til3 antibody, tlr-5 antibody, tlr5 antibody, toll like receptor 5 antibody, toll-like receptor 5 antibody, toll like receptor 5 L homeolog antibody, toll-like receptor 5b antibody, TLR5 antibody, Tlr5 antibody, tlr5.L antibody, tlr-5 antibody, tlr5b antibody
    Background
    TLR5 encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.

    Synonyms: FLJ10052 antibody|MGC126430 antibody|MGC126431 antibody|SLEB1 antibody|TIL 3 antibody|TIL3 antibody|TLR 5 antibody|Tlr5 antibody|TLR5_HUMAN antibody|Toll like receptor 5 antibody| Toll like receptor 5 precursor antibody|Toll-like receptor 5 antibody|Toll/interleukin 1 receptor like protein 3 antibody|Toll/interleukin-1 receptor-like protein 3 antibody
    Gene ID
    7100
    UniProt
    O60602
    Pathways
    TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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