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PSCA antibody (AA 21-95)

PSCA Reactivity: Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3043554
  • Target See all PSCA Antibodies
    PSCA (Prostate Stem Cell Antigen (PSCA))
    Binding Specificity
    • 15
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-95
    Reactivity
    • 54
    • 19
    • 10
    • 2
    • 2
    • 2
    Mouse, Rat
    Host
    • 44
    • 9
    • 1
    Rabbit
    Clonality
    • 46
    • 8
    Polyclonal
    Conjugate
    • 33
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSCA antibody is un-conjugated
    Application
    • 47
    • 20
    • 13
    • 13
    • 12
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Prostate stem cell antigen(PSCA) detection. Tested with WB in Human,Mouse,Rat.
    Cross-Reactivity (Details)
    Predicted Cross Reactivity: human
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Characteristics
    Rabbit IgG polyclonal antibody for Prostate stem cell antigen(PSCA) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: prostate stem cell antigen
    Protein Name: Prostate stem cell antigen
    Purification
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human PSCA recombinant protein (Position: L21-S95). Human PSCA shares 66% amino acid (aa) sequence identity with mouse PSCA.
    Isotype
    IgG
    Top Product
    Discover our top product PSCA Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, The detection limit for PSCA is approximately 0.1 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Wang, Wu, Zhu, Ding, Cai, Ni, Wu, Meng, Zhang, Zhang, Li, Wang, Chen, Jin, Zhang: "PSCA rs2294008 polymorphism contributes to the decreased risk for cervical cancer in a Chinese population." in: Scientific reports, Vol. 6, pp. 23465, (2017) (PubMed).

    Zhao, Ma, Zeng, Qi, Ou, Liang: "Small interference RNA-mediated silencing of prostate stem cell antigen attenuates growth, reduces migration and invasion of human prostate cancer PC-3M cells." in: Urologic oncology, Vol. 31, Issue 3, pp. 343-51, (2013) (PubMed).

  • Target
    PSCA (Prostate Stem Cell Antigen (PSCA))
    Alternative Name
    PSCA (PSCA Products)
    Synonyms
    PRO232 antibody, 2210408B04Rik antibody, PSCA antibody, prostate stem cell antigen antibody, PSCA antibody, Psca antibody, LOC482068 antibody
    Background
    PSCA is also known as PRO232. This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals, this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.

    Synonyms: PRO 232 antibody|PRO232 antibody|Prostate stem cell antigen antibody
    Gene ID
    8000
    UniProt
    O43653
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