Parvin alpha antibody (Middle Region)

Catalog No. ABIN3043590

The Rabbit Polyclonal anti-Parvin alpha antibody (ABIN3043590) specifically detects Parvin alpha in WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Parvin alpha antibody (Middle Region) (ABIN3043590)

Target: Parvin alpha (PARVA) (Parvin, alpha (PARVA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Parvin alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Parvin alpha Antibody

Binding Specificity: AA 155-185, Middle Region

Purpose: Anti-Parvin alpha/PARVA Antibody

Sequence: QKLQTVLEKI NETLKLPPRS IKWNVDSVHA K

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Parvin alpha/PARVA Antibody (ABIN3043590). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Parvin alpha, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for Parvin alpha

Target: Parvin alpha (PARVA) (Parvin, alpha (PARVA))

Alternative Name: PARVA

Background:

Synonyms: Alpha-parvin,Actopaxin,CH-ILKBP,Calponin-like integrin-linked kinase-binding protein,Matrix-remodeling-associated protein 2,PARVA,MXRA2,

Tissue Specificity: Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. .

Background: Parvin alpha is a protein that in humans is encoded by the PARVA gene. It is located on 11p15.3. PARVA belongs to the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival.

Sequence Similarities: Belongs to the parvin family.

Molecular Weight: 42 kDa

Gene ID: 55742

Pathways: Smooth Muscle Cell Migration