MUC4 antibody (AA 1249-1444)

Catalog No. ABIN3043595

Product Details anti-MUC4 Antibody

Target: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Binding Specificity: AA 1249-1444

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Mucin-4(MUC4) detection. Tested with WB in Human,Rat.

Cross-Reactivity (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Mucin-4(MUC4) detection. Tested with WB in Human,Rat.
Gene Name: mucin 4, cell surface associated
Protein Name: Mucin-4

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MUC4 recombinant protein (Position: M1249-D1444). Human MUC4 shares 69% and 36% amino acid (aa) sequences identity with mouse and rat MUC4, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, The detection limit for MUC4 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for MUC4

Target: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Alternative Name: MUC4 (MUC4 Products)

Synonyms: 4933405I11Rik antibody, Asgp antibody, ASGP antibody, HSA276359 antibody, MUC-4 antibody, ASGP-1 antibody, Psmc antibody, mucin 4 antibody, mucin 4, cell surface associated antibody, Muc4 antibody, MUC4 antibody

Background: Mucin 4, also known as MUC4, is a mucin protein that in humans is encoded by the MUC4 gene. Like other mucins, Mucin 4 is a high-molecular weight glycoprotein. It is mapped to 3q29. In normal functioning, Mucin 4 is known to play anti-adhesive roles in the body, such as in lubricating the reproductive lining. It is found in the respiratory tract, particularly in the trachea and lung and the digestive tract, in the esophagus and colon, as well as in the visual and auditory systems. Mucin 4 serves to protect and lubricate the epithelium, which facilitates transport and traps foreign particles. It is found to be overexpressed during the luteal phase of menstruation. Mucin 4 may also have a role in fetal morphogenic development.

Synonyms: Ascites sialoglycoprotein 1 antibody|Ascites sialoglycoprotein 2 antibody|Ascites sialoglycoprotein antibody|ASGP antibody|ASGP-1 antibody|ASGP-2 antibody|HSA276359 antibody|MUC-4 antibody|Muc4 antibody|MUC4_HUMAN antibody|Mucin 4 antibody|Mucin 4 cell surface associated antibody|Mucin 4 tracheobronchial antibody|Mucin-4 beta chain antibody|Pancreatic adenocarcinoma mucin antibody|Testis mucin antibody|Tracheobronchial mucin antibody|Tracheobronchial mucin Fragment antibody

Gene ID: 4585

UniProt: Q99102

Pathways: Regulation of Leukocyte Mediated Immunity