CCR6 antibody (C-Term)
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- Target See all CCR6 Antibodies
- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
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Binding Specificity
- AA 358-374, C-Term
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CCR6 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit IgG polyclonal antibody for C-C chemokine receptor type 6(CCR6) detection. Tested with WB in Human,Mouse,Rat.
- Sequence
- RQTSETADND NASSFTM
- Cross-Reactivity (Details)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Characteristics
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Rabbit IgG polyclonal antibody for C-C chemokine receptor type 6(CCR6) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: chemokine(C-C motif) receptor 6
Protein Name: C-C chemokine receptor type 6(C-C CKR-6/CC-CKR-6/CCR-6) - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human CCR6(358-374aa RQTSETADNDNASSFTM), different from the related rat and mouse sequences by two amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product CCR6 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Preservative
- Thimerosal (Merthiolate), Sodium azide
- Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
- Alternative Name
- CCR6 (CCR6 Products)
- Synonyms
- BN-1 antibody, C-C CKR-6 antibody, CC-CKR-6 antibody, CCR-6 antibody, CD196 antibody, CKR-L3 antibody, CKRL3 antibody, CMKBR6 antibody, DCR2 antibody, DRY6 antibody, GPR29 antibody, GPRCY4 antibody, STRL22 antibody, Cmkbr6 antibody, KY411 antibody, C-C motif chemokine receptor 6 antibody, chemokine (C-C motif) receptor 6 antibody, CCR6 antibody, Ccr6 antibody
- Background
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CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis.
Synonyms: BN 1 antibody|BN1 antibody|C C chemokine receptor type 6 antibody|C C CKR 6 antibody|C-C chemokine receptor type 6 antibody|C-C CKR-6 antibody|CC chemokine receptor type 6 antibody|CC CKR 6 antibody|CC R6 antibody|CC-CKR-6 antibody|CCCKR6 antibody|CCR 6 antibody|CCR-6 antibody|Ccr6 antibody|CCR6_HUMAN antibody|CD 196 antibody|CD196 antibody|CD196 antigen antibody|Chemokine(C C motif) receptor 6 antibody|Chemokine(C C) receptor 6 antibody|Chemokine(CC motif) receptor 6 antibody|Chemokine(CC) receptor 6 antibody|Chemokine receptor 6 antibody|Chemokine receptor like 3 antibody|Chemokine receptor-like 3 antibody|CKR 6 antibody|CKR L3 antibody|CKR-L3 antibody|CKR6 antibody|CKRL3 antibody|CMKBR6 antibody|CMKBR6 antibody|DCR 2 antibody|DCR2 antibody|DRY 6 antibody|DRY6 antibody|G protein coupled receptor 29 antibody|G-protein coupled receptor 29 antibody|GPR 29 antibody|GPR CY4 antibody|GPR-CY4 antibody|GPR29 antibody|GPRCY 4 antibody|GPRCY4 antibody|LARC receptor antibody|Seven transmembrane receptor lymphocyte 22 antibody|STRL 22 antibody|STRL22 antibody - UniProt
- P51684
- Pathways
- cAMP Metabolic Process
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