BMP6 antibody (C-Term)

Catalog No. ABIN3043760

Product Details anti-BMP6 Antibody

Target: BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Binding Specificity: AA 383-419, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit IgG polyclonal antibody for Bone morphogenetic protein 6(BMP6) detection. Tested with WB, ELISA in Human.

Sequence: QSRNRSTQSQ DVARVSSASD YNSSELKTAC RKHELYV

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Bone morphogenetic protein 6(BMP6) detection. Tested with WB, ELISA in Human.
Gene Name: bone morphogenetic protein 6
Protein Name: Bone morphogenetic protein 6

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human BMP6 (383-419aa QSRNRSTQSQDVARVSSASDYNSSELKTACRKHELYV), different from the related mouse sequence by six amino acids, and from the related rat sequence by three amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-BMP6 antibody (ABIN3043760)

Tang, Li, Yu, Gao, Liu, Chen, Xing, Liu, Yao: "Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway." in: The Journal of nutritional biochemistry, Vol. 25, Issue 6, pp. 675-82, (2014) (PubMed).

Target Details for BMP6

Target: BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Alternative Name: BMP6 (BMP6 Products)

Synonyms: BMP6 antibody, zgc:113595 antibody, vgr antibody, vgr-1 antibody, vgr1 antibody, VGR antibody, VGR1 antibody, D13Wsu115e antibody, Vgr1 antibody, bone morphogenetic protein 6 antibody, bone morphogenetic protein 6 S homeolog antibody, BMP6 antibody, bmp6 antibody, bmp6.S antibody, Bmp6 antibody

Background: Bone morphogenetic protein 6 is a protein that in humans is encoded by the BMP6 gene. It is mapped to 6p24-p23. The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Synonyms: BMP-6 antibody|Bmp6 antibody|BMP6_HUMAN antibody|Bone morphogenetic protein 6 antibody|Bone Morphogenic Protein 6 antibody| Decapentaplegic vegetal related antibody|DVR6 antibody|HGNC:12686 antibody|TGFB related vegetal related growth factor antibody| Transforming growth factor beta antibody|Vegetal related (TGFB related) cytokine antibody|Vegetal related growth factor (TGFB related) antibody|Vg related sequence antibody|VG-1-R antibody|VG-1-related protein antibody|Vg1 related sequence antibody|VGR antibody|VGR-1 antibody|VGR1 antibody

Gene ID: 654

UniProt: P22004

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process