ADAMTS1 antibody (C-Term)

Catalog No. ABIN3044070

The Rabbit Polyclonal anti-ADAMTS1 antibody (ABIN3044070) specifically detects ADAMTS1 in WB. The antibody is reactive with Rat and Mouse samples.

Quick Overview for ADAMTS1 antibody (C-Term) (ABIN3044070)

Target: ADAMTS1 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAMTS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADAMTS1 Antibody

Binding Specificity: AA 956-968, C-Term

Purpose: Anti-ADAMTS1 Antibody

Sequence: KHYIDFCTLT QCS

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-ADAMTS1 Antibody (ABIN3044070). Tested in WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse ADAMTS1, different from the related rat sequence by one amino acid, and from the related human sequence by four amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Rat, Mouse

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ADAMTS1

Target: ADAMTS1 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1))

Alternative Name: ADAMTS1

Background:

Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 1,ADAM-TS 1,ADAM-TS1,ADAMTS-1,3.4.24.-,Adamts1,

Tissue Specificity: Expressed in many normal organ tissues and several cancer cell lines.

Background: A disintegrin and metalloproteinase with thrombospondin motifs 1 is an enzyme that in humans is encoded by the ADAMTS1 gene. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.

Sequence Similarities: Contains 1 disintegrin domain.

Molecular Weight: 105 kDa

UniProt: P97857

Pathways: SARS-CoV-2 Protein Interactome