GATA2 antibody (N-Term)
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- Target See all GATA2 Antibodies
- GATA2 (GATA Binding Protein 2 (GATA2))
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Binding Specificity
- AA 46-60, N-Term
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GATA2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit IgG polyclonal antibody for Endothelial transcription factor GATA-2(GATA2) detection. Tested with WB in Human,Mouse,Rat.
- Sequence
- DVFFNHLDSQ GNPYY
- Cross-Reactivity (Details)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Characteristics
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Rabbit IgG polyclonal antibody for Endothelial transcription factor GATA-2(GATA2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: GATA binding protein 2
Protein Name: Endothelial transcription factor GATA-2 - Purification
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human GATA2(46-60aa DVFFNHLDSQGNPYY), identical to the related rat and mouse sequences.
- Isotype
- IgG
- Top Product
- Discover our top product GATA2 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for GATA2 is approximately 5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Preservative
- Thimerosal (Merthiolate), Sodium azide
- Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Expiry Date
- 12 months
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- Target
- GATA2 (GATA Binding Protein 2 (GATA2))
- Alternative Name
- GATA2 (GATA2 Products)
- Synonyms
- DCML antibody, MONOMAC antibody, NFE1B antibody, Gata-2 antibody, xgata-2 antibody, xgata2 antibody, GATA-2 antibody, NF-E1b antibody, GATA2 antibody, Gata2 antibody, gata2 antibody, zg2 antibody, zgc:91840 antibody, GATA binding protein 2 antibody, GATA binding protein 2 L homeolog antibody, amidase antibody, glutamyl/aspartyl-tRNA(Gln/Asp) amidotransferasesubunit A antibody, hypothetical protein antibody, glutamyl-tRNA(Gln) amidotransferase, subunit GatA (Glu-ADT subunit A) antibody, GATA2 transcription factor antibody, putative gata binding factor antibody, GATA binding protein 2a antibody, GATA binding protein 2b antibody, GATA2 antibody, Gata2 antibody, gata2.L antibody, RR_RS20245 antibody, gatA2 antibody, Smp_018590 antibody, gata2a antibody, gata2b antibody
- Background
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GATA2(GATA binding protein 2) is a human gene which makes a protein called GATA binding protein 2 - a transcription factor. The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells. Ciciotte et al.(1997)mapped the mouse Gata2 gene to chromosome 6 by study of DNA from an interspecific backcross panel. They pointed out that the human gene had been mapped to chromosome 3 by Dorfman et al.(1992) using DNA from a panel of 12 rodent/human hybrids containing various human chromosomes and applying Southern blot analysis. By exon trapping using a PAC contig spanning a breakpoint region associated with myeloid leukemia, Wieser et al.(2000) mapped the GATA2 gene to chromosome 3q21. GATA2 is transcribed from telomere to centromere. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.
Synonyms: DCML antibody|Endothelial transcription factor GATA 2 antibody|Endothelial transcription factor GATA-2 antibody|Endothelial transcription factor GATA2 antibody|FLJ45948 antibody|GATA 2 antibody|GATA Binding Protein 2 antibody|GATA-binding protein 2 antibody|Gata2 antibody|GATA2_HUMAN antibody|MGC2306 antibody|MONOMAC antibody|NFE 1B antibody|NFE1B antibody|OTTHUMP00000216240 antibody - UniProt
- P23769
- Pathways
- Stem Cell Maintenance
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