Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

VEGFD antibody (Middle Region)

Figf Reactivity: Human, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3044291
  • Target See all VEGFD (Figf) Antibodies
    VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
    Binding Specificity
    • 19
    • 10
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-115, Middle Region
    Reactivity
    • 67
    • 21
    • 15
    • 2
    • 1
    • 1
    Human, Rat
    Host
    • 56
    • 16
    • 1
    Rabbit
    Clonality
    • 56
    • 17
    Polyclonal
    Conjugate
    • 39
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VEGFD antibody is un-conjugated
    Application
    • 58
    • 35
    • 30
    • 11
    • 11
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for Vascular endothelial growth factor D(FIGF) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Sequence
    VIDEEWQRTQ CSPRE
    Cross-Reactivity (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Characteristics
    Rabbit IgG polyclonal antibody for Vascular endothelial growth factor D(FIGF) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: c-fos induced growth factor(vascular endothelial growth factor D)(VEGF-D)
    Protein Name: Vascular endothelial growth factor D
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human VEGFD(101-115aa VIDEEWQRTQCSPRE), identical to the related rat and mouse sequences.
    Isotype
    IgG
    Top Product
    Discover our top product Figf Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Preservative
    Thimerosal (Merthiolate), Sodium azide
    Precaution of Use
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Expiry Date
    12 months
  • Qi, Du, Chen, Chen, Yi, Chen, Wen, Wei, Zhao: "VEGF-D-enhanced lymph node metastasis of ovarian cancer is reversed by vesicular stomatitis virus matrix protein." in: International journal of oncology, Vol. 49, Issue 1, pp. 123-32, (2017) (PubMed).

  • Target
    VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))
    Alternative Name
    VEGF-D (Figf Products)
    Synonyms
    FIGF antibody, vegfd antibody, vegf-d antibody, VEGFD antibody, AI325264 antibody, VEGF-D antibody, Vegfd antibody, Vegf-d antibody, vascular endothelial growth factor D antibody, Vascular endothelial growth factor D antibody, VEGFD antibody, vegfd antibody, vegfd.L antibody, Vegfd antibody
    Background
    C-fos induced growth factor(FIGF)(or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded by the FIGF gene. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor(PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. Analyzing by Northern blotting, Yamada et al.(1997) symbolized VEGFD, was expressed as a 2.2-kb transcript with highest expression in lung, heart, small intestine, and fetal lung, and lower levels in skeletal muscle, colon, and pancreas. And Achen et al.(1998) concluded that VEGFD was most closely related to VEGFC by virtue of the presence of N- and C-terminal extensions that were not found in other VEGF family members. Stacker et al.(2001) showed that VEGFD can induce tumor angiogenesis through VEGFR2 and tumor lymphangiogenesis through VEGFR3, whereas VEGF, which does not activate VEGFR3, induces only tumor angiogenesis.

    Synonyms: c-fos induced growth factor antibody|c-fos induced growth factor(vascular endothelial growth factor D) antibody|c-fos-induced growth factor antibody|FIGF antibody|Vascular endothelial growth factor D antibody|Vascular endothelial growth factor D precursor antibody|VEGF D antibody|VEGF-D antibody|VEGFD antibody|VEGFD_HUMAN antibody
    UniProt
    O43915
    Pathways
    RTK Signaling
You are here:
Support