ONECUT1 antibody (N-Term)

Catalog No. ABIN3044467

This Rabbit Polyclonal antibody specifically detects ONECUT1 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ONECUT1 antibody (N-Term) (ABIN3044467)

Target: ONECUT1 (One Cut Homeobox 1 (ONECUT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ONECUT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ONECUT1 Antibody

Binding Specificity: AA 187-203, N-Term

Purpose: Anti-HNF6/ONECUT1 Antibody

Sequence: LGSIHNSQQG LPHYAHP

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-HNF6/ONECUT1 Antibody (ABIN3044467). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human HNF6, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.01 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ONECUT1

Target: ONECUT1 (One Cut Homeobox 1 (ONECUT1))

Alternative Name: ONECUT1

Background:

Synonyms: Hepatocyte nuclear factor 6,HNF-6,One cut domain family member 1,One cut homeobox 1,ONECUT1,HNF6, HNF6A,

Tissue Specificity: Highly expressed in liver, lower expression in testis and skin.

Background: One cut homeobox 1 (ONECUT1), also called Hepatocyte nuclear factor 6 (HNF6) is found strong expression in liver and lower expression in testis and skin. ONECUT1 gene is mapped to 15q21.3. This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer.

Sequence Similarities: Belongs to the CUT homeobox family.

Molecular Weight: 55 kDa