SLC9A2 antibody (C-Term)

Catalog No. ABIN3044468

The Rabbit Polyclonal anti-SLC9A2 antibody is suitable to detect SLC9A2 in samples from Human, Rat and Mouse. It has been validated for WB and IHC.

Quick Overview for SLC9A2 antibody (C-Term) (ABIN3044468)

Target: SLC9A2 (Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 2 (SLC9A2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC9A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SLC9A2 Antibody

Binding Specificity: AA 666-684, C-Term

Purpose: Anti-Sodium/hydrogen exchanger 2 SLC9A2 Antibody

Sequence: RYLSLPKNTK LPEKLQKRR

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Sodium/hydrogen exchanger 2 SLC9A2 Antibody (ABIN3044468). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SLC9A2, different from the related rat and mouse sequences by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SLC9A2

Target: SLC9A2 (Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 2 (SLC9A2))

Alternative Name: SLC9A2

Background:

Synonyms: Sodium/hydrogen exchanger 2;Na (+)/H (+) exchanger 2;NHE-2;Solute carrier family 9 member 2;SLC9A2;NHE2;

Tissue Specificity: Expressed in skeletal muscle, colon and kidney. Lower levels in the testis, prostate, ovary, and small intestine.

Background: Sodium–hydrogen exchanger 2, also called SLC9A2 or NHE2 is a protein that in humans is encoded by the SLC9A2 gene. This gene is mapped to 2q12.1. The Na+/H+ exchangers (NHE) are membrane proteins involved in cell volume. The exchanger (which they called NHE2) is found in several tissues, including intestine and kidney, and is highly expressed in villus and distal convoluted tubules. This gene is involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. It seems to play an important role in colonic sodium absorption.

Sequence Similarities: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

Molecular Weight: 91 kDa

Pathways: Proton Transport