SLC9A2 antibody (C-Term)

Catalog No. ABIN3044468

Product Details anti-SLC9A2 Antibody

Target: SLC9A2 (Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 2 (SLC9A2))

Binding Specificity: AA 666-684, C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC9A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Sodium/hydrogen exchanger 2(SLC9A2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequence: RYLSLPKNTK LPEKLQKRR

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Sodium/hydrogen exchanger 2(SLC9A2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: solute carrier family 9, subfamily A(NHE2, cation proton antiporter 2), member 2
Protein Name: Sodium/hydrogen exchanger 2

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SLC9A2(666-684aa RYLSLPKNTKLPEKLQKRR), different from the related rat and mouse sequences by two amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SLC9A2

Target: SLC9A2 (Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 2 (SLC9A2))

Alternative Name: SLC9A2 (SLC9A2 Products)

Synonyms: NHE2 antibody, Nhe2 antibody, 2210416H12Rik antibody, 4932415O19Rik antibody, AV333884 antibody, SLC9A2 antibody, NHE-2 antibody, si:dkey-4e7.1 antibody, solute carrier family 9 member A2 antibody, solute carrier family 9 (sodium/hydrogen exchanger), member 2 antibody, putative sodium/hydrogen exchanger 2 (nhe2) antibody, sodium/hydrogen exchanger 2-like antibody, solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 antibody, SLC9A2 antibody, Slc9a2 antibody, Smp_146740 antibody, LOC100346147 antibody, slc9a2 antibody

Background: Sodium-hydrogen exchanger 2, also called SLC9A2 or NHE2 is a protein that in humans is encoded by the SLC9A2 gene. This gene is mapped to 2q12.1. The Na+/H+ exchangers(NHE) are membrane proteins involved in cell volume. The exchanger(which they called NHE2) is found in several tissues, including intestine and kidney, and is highly expressed in villus and distal convoluted tubules. This gene is involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. It seems to play an important role in colonic sodium absorption.

Synonyms: H7 antibody|Na(+)/H(+) exchanger 2 antibody|NHE 2 antibody|NHE-2 antibody|NHE2 antibody|SL9A2_HUMAN antibody|Slc9a2 antibody|Sodium/hydrogen exchanger antibody|Sodium/hydrogen exchanger 2 antibody|Solute carrier family 9(sodium/hydrogen exchanger), member 2 antibody|Solute carrier family 9 member 2 antibody|Solute carrier family 9, member 2 antibody

Pathways: Proton Transport