Adipsin antibody (AA 30-235)
Quick Overview for Adipsin antibody (AA 30-235) (ABIN3044505)
Target
See all Adipsin (CFD) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 30-235
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Purpose
- Anti-Factor D/CFD Antibody Picoband®
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins.
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Characteristics
- Anti-Factor D/CFD Antibody Picoband® (ABIN3044505). Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Purification
- Immunogen affinity purified.
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Immunogen
- E. coli-derived mouse Factor D recombinant protein (Position: Q30-K235). Mouse Factor D shares 66.5% and 87.4% amino acid (aa) sequence identity with human and rat Factor D, respectively.
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Isotype
- IgG
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Application Notes
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Western blot, 0.1-0.5 μg/mL, Mouse
1. Biesma, D. H., Hannema, A. J., van Velzen-Blad, H., Mulder, L., van Zwieten, R., Kluijt, I., Roos, D. A family with complement factor D deficiency. J. Clin. Invest. 108: 233-240, 2001. 2. Ronti T, Lupattelli G, Mannarino E (April 2006). "The endocrine function of adipose tissue: an update". Clin. Endocrinol. (Oxf) 64 (4): 355-65. 3. Volanakis JE, Narayana SV (April 1996). "Complement factor D, a novel serine protease". Protein Sci. 5 (4): 553-64. -
Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Adipsin (CFD) (Complement Factor D (CFD))
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Alternative Name
- Cfd
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Background
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Synonyms: Complement factor D,3.4.21.46,28 kDa adipocyte protein,Adipsin,C3 convertase activator,Properdin factor D,Cfd,Adn, Df,
Tissue Specificity: Present only in testis (at protein level). .
Background: Factor D is a?protein?which in humans is encoded by the?CFD?gene. The protein encoded by this gene is a member of the?trypsin?family of peptidases. The encoded protein is a component of the?alternative complement pathway?best known for its role in humoral suppression of infectious agents. It is also a serine protease that is secreted by?adipocytes?into the bloodstream. And it stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
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Molecular Weight
- 43 kDa
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Gene ID
- 11537
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UniProt
- P03953
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Pathways
- Complement System
Target
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