RNH1 antibody (N-Term)

Catalog No. ABIN3044540

Product Details anti-RNH1 Antibody

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Binding Specificity: AA 2-37, N-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNH1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Ribonuclease inhibitor(RNH1) detection. Tested with WB in Human,Mouse,Rat.

Sequence: SLDIQSLDIQ CEELSDARWA ELLPLLQQCQ VVRLDD

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Ribonuclease inhibitor(RNH1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: ribonuclease/angiogenin inhibitor 1
Protein Name: Ribonuclease inhibitor

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human RNH1 (2-37aa SLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDD), different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for RNH1

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Alternative Name: RNH1 (RNH1 Products)

Synonyms: RAI antibody, RNH antibody, AW546468 antibody, C80305 antibody, RNH1 antibody, Rnh antibody, Rnh1 antibody, im:7039360 antibody, si:ch211-213a13.3 antibody, wu:fd55g05 antibody, ribonuclease/angiogenin inhibitor 1 antibody, ribonuclease inhibitor antibody, RNH1 antibody, Rnh1 antibody, Tc00.1047053511893.10 antibody, Tc00.1047053507583.70 antibody, rnh1 antibody

Background: Ribonuclease inhibitor is an enzyme that in humans is encoded by the RNH1 gene. Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular Rnases. In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin. Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover, the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.

Synonyms: AW546468 antibody|C80305 antibody|MGC18200 antibody|MGC4569 antibody|MGC54054 antibody|OTTHUMP00000147628 antibody|OTTHUMP00000229864 antibody|OTTHUMP00000229865 antibody|OTTHUMP00000229866 antibody|OTTHUMP00000229870 antibody|OTTHUMP00000229871 antibody| OTTHUMP00000229872 antibody|Placental ribonuclease inhibitor antibody|Placental RNase inhibitor antibody|PRI antibody|RAI antibody|RI antibody|Ribonuclease inhibitor antibody|Ribonuclease/angiogenin inhibitor 1 antibody|Ribonuclease/angiogenin inhibitor antibody| RINI_HUMAN antibody|RNase inhibitor antibody|RNH 1 antibody|RNH antibody|RNH1 antibody|Rnh1 ribonuclease/angiogenin inhibitor 1 antibody

Gene ID: 6050

UniProt: P13489