D-Dimer (Fibrin Degradation Product) antibody

Catalog No. ABIN305022

The Mouse Monoclonal anti-D-Dimer (Fibrin Degradation Product) antibody (Clone DD1) (ABIN305022) specifically detects D-Dimer (Fibrin Degradation Product) in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for D-Dimer (Fibrin Degradation Product) antibody (ABIN305022)

Target: D-Dimer (Fibrin Degradation Product)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Clone: DD1

Product Details

Specificity: Specific for human D-dimer and high molecular weight fibrin degradation products, but does not cross-react with fibrinogen (D-monomer). D-dimers are the principle degradation products of cross-linked fibrin, released into the bloodstream following the digestion of fibrin clots (thrombus) by the enzyme plasmin, and thus measurement of the level of D-dimer in plasma, can be used as an indication of thrombotic disorders. Conditions in which levels of D-dimer are elevated include deep vein thrombosis (DVT), venous thromboembolism (VTE), cardiovascular disease and disseminated intravascular coagulation (DIC), a possible acute condition arising from surgical operations, septic shock and liver disease. Can be used as the capture antibody in matched pair ELISA for the detection of D-dimer in human plasma. Plasma samples must be diluted with 10 mM Tris-HCl buffer,  pH 7.5, containing 1 M NaCl (final concentration in sample >0.5 M) and 0.1 % Tween 20.

Purification: Affinity purified

Immunogen: Homogenized fibrin clot.

Isotype: IgG2a

Application Details

Application Notes: Approved: ELISA, WB

Usage: ELISA: This product may be used in an indirect ELISA or as the capture antibody in sandwich ELISA in conjunction with the antibodies clone DD6 (LS-C58116), clone DD4 (LS-C58114) or clone DD5 (LS-C58115), for the detection of D-dimer in human plasma. Plasma samples must be diluted with 10 mM Tris-HCl buffer,  pH 7.5, containing 1 M NaCl (final concentration in sample >0.5 M) and 0.1 % Tween 20.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details

Target: D-Dimer (Fibrin Degradation Product)

Alternative Name: Fibrin Degradation Product D-Dimer