D-Dimer (Fibrin Degradation Product) antibody

Catalog No. ABIN305042

The Mouse Monoclonal anti-D-Dimer (Fibrin Degradation Product) antibody is suitable to detect D-Dimer (Fibrin Degradation Product) in samples from Human. It has been validated for WB and ELISA.

Quick Overview for D-Dimer (Fibrin Degradation Product) antibody (ABIN305042)

Target: D-Dimer (Fibrin Degradation Product)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Clone: DD5

Product Details

Specificity: Recognizes human D-dimer and shows low cross-reactivity with fibrinogen (D-monomer). D-dimers are the principle degradation products of cross-linked fibrin, released into the bloodstream following the digestion of fibrin clots (thrombus) by the enzyme plasmin, and thus measurement of the level of D-dimer in plasma, can be used as an indication of thrombotic disorders. Conditions in which levels of D-dimer are elevated include deep vein thrombosis (DVT), venous thromboembolism (VTE), cardiovascular disease and disseminated intravascular coagulation (DIC), a possible acute condition arising from surgical operations, septic shock and liver disease. Can be used as the detection antibody in ELISA for the detection of D-dimer in human plasma. Plasma samples must be diluted with 10 mM Tris-HCl buffer,  pH 7.5, containing 1 M NaCl (final concentration in sample >0.5 M) and 0.1 % Tween 20.

Purification: Affinity purified

Immunogen: Homogenized fibrin clot.

Isotype: IgG2b

Application Details

Application Notes: Approved: ELISA, WB

Usage: ELISA: This product may be used in an indirect ELISA or as a detection antibody in a sandwich ELISA together with clone DD1 (product code LS-C58035), for the detection of D-dimer in human plasma. Plasma samples must be diluted with 10 mM Tris-HCl buffer,  pH 7.5, containing 1 M NaCl (final concentration in sample >0.5 M) and 0.1 % Tween 20.WESTERN BLOT: Please note that non-reducing conditions are required for detection of the D-dimer.

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details

Target: D-Dimer (Fibrin Degradation Product)

Alternative Name: Fibrin Degradation Product D-Dimer