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HLA-ABC antibody

This anti-HLA-ABC antibody is a Rat Monoclonal antibody detecting HLA-ABC in FACS, IP, IHC (fro) and IHC. Suitable for Human.
Catalog No. ABIN305193

Quick Overview for HLA-ABC antibody (ABIN305193)

Target

See all HLA-ABC Antibodies
HLA-ABC

Reactivity

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Human

Host

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Rat

Clonality

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Monoclonal

Conjugate

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This HLA-ABC antibody is un-conjugated

Application

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC)

Clone

YTH862-2
  • Specificity

    Recognizes a monomorphic determinant on the human HLA Class I heavy chain. Epitope analysis has shown that this binds in the alpha1 domain. MHC Class I is expressed by all nucleated cells. Recent studies have shown that this may be able to induce apoptosis in activated but not resting T cells.

    No Cross-Reactivity

    Mouse (Murine)

    Purification

    Affinity purified

    Immunogen

    PHA activated human peripheral blood lymphocytes.

    Type of Immunogen: Cells

    Isotype

    IgG2b
  • Application Notes

    Approved: Flo (1:50 - 1:100), IHC, IHC-Fr, IP

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS,  pH 7.4, 0.09 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target

    HLA-ABC

    Alternative Name

    HLA-A/B/C

    Pathways

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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