HLA-ABC antibody
Quick Overview for HLA-ABC antibody (ABIN305193)
Target
See all HLA-ABC AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Recognizes a monomorphic determinant on the human HLA Class I heavy chain. Epitope analysis has shown that this binds in the alpha1 domain. MHC Class I is expressed by all nucleated cells. Recent studies have shown that this may be able to induce apoptosis in activated but not resting T cells.
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No Cross-Reactivity
- Mouse (Murine)
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Purification
- Affinity purified
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Immunogen
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PHA activated human peripheral blood lymphocytes.
Type of Immunogen: Cells -
Isotype
- IgG2b
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Application Notes
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Approved: Flo (1:50 - 1:100), IHC, IHC-Fr, IP
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- HLA-ABC
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Alternative Name
- HLA-A/B/C
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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