CSTB antibody (AA 1-98)

Catalog No. ABIN306448

This Mouse Monoclonal antibody specifically detects CSTB in WB, ELISA, ICC and IF. It exhibits reactivity toward Human.

Quick Overview for CSTB antibody (AA 1-98) (ABIN306448)

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSTB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 2F1

Product Details anti-CSTB Antibody

Binding Specificity: AA 1-98

Purpose: Human Cystatin B antibody

Purification: Purified

Immunogen: Recombinant human CSTB (1-98aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Application Notes: Recommended dilution 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for CSTB

Target: CSTB (Cystatin B (Stefin B) (CSTB))

Alternative Name: Cystatin B

Background: CSTB, also known as Cystatin B is an anti-protease implicated in myoclonus epilepsy, a degenerative disease of the central nervous system. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. This protein is able to from a dimer stabilized by noncovalent forces and is thought to play a role in protecting against the proteases leaking from lysosomes in cells. CSTB is located in the lysosomes and the cytoplasm, but also in the nucleus.

NCBI Accession: NP_000091

Pathways: Response to Water Deprivation