Calcium Channel Alpha2/delta Subunit antibody

Catalog No. ABIN306883

This Rabbit Polyclonal antibody specifically detects Calcium Channel Alpha2/delta Subunit in WB. It exhibits reactivity toward Human and Rat.

Quick Overview for Calcium Channel Alpha2/delta Subunit antibody (ABIN306883)

Target: Calcium Channel Alpha2/delta Subunit

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Product Details

Purpose: Rabbit anti Rat calcium channel alpha2/delta subunit

Cross-Reactivity: Human, Rat

Characteristics: The calcium channel alpha2/delta subunit is a glycosylated structural subunit consisting of the alpha2 subunit and the delta peptide. There is distinctive alpha2 subunit expression in rat spinal cord and dorsal root ganglia (DRG) There are two forms of the alpha2 subunit in DRG that are different from the alpha2 subunit in other tissues examined, at least at the glycosylation level. Thus, post-translational modification may be important in tissue specific and functional expression of the alpha2/delta subunit (2). alpha2/delta and beta1b interact with alpha1G to increase trafficking of, or stabilize, functional alpha1G channels expressed at the plasma membrane.(3)

Purification: Ammonium Sulfate Precipitation

Immunogen: Synthetic peptide derived from the rat alpha2/delta calcium channel conjugated to KLH

Isotype: IgG

Application Details

Application Notes: This antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details

Target: Calcium Channel Alpha2/delta Subunit

UniProt: Q8VHS9