Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) (N-Term) antibody

Catalog No. ABIN306909

The Rabbit Polyclonal anti-Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) antibody (ABIN306909) specifically detects Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) in WB. The antibody is reactive with Human samples.

Quick Overview for Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) (N-Term) antibody (ABIN306909)

Target: Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Purpose: Rabbit anti Human Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) CT

Cross-Reactivity: Human

Characteristics: EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG4 is lysophospholipid. There are 6 known members of the EDG receptor family and they are implicated in mediating growthrelated effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor and leukocyte containing tissues.

Purification: Ammonium Sulfate Precipitation

Immunogen: Antibody raised against a unique synthetic peptide derived from the N-terminal of the human EDG4 protein. Antigen sequence differs in mouse and rat by one amino acid.

Isotype: IgG

Application Details

Application Notes: This antibody can be used for Western blotting (5-10 μg/mL). Western blot should be visualized using a high sensitivity secondary/substrate system (i.e. Pierce's SuperSignal West Femto Maximum Sensitivity Substrate). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details

Target: Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4)

UniProt: Q9HBW0